DNA goes to School conducts workshops that are held in schools and universities. The equipment and materials are provided by DNA goes to School. Our equipment fits in a small toolbox, making transportation to different locations easy and convenient.

The basic workshop consists of 4 modules of 3 hours each (total of 12 hours). Each module explores a different topic and includes hands-on activities and debates. All discussions are conducted with the support of articles presenting different aspects and points of views. The role of our instructors is to introduce the subject, start a discussion and conduct an open and pluralistic debate.

We are all made of DNA
In the first module participants learn how to use automatic pipettes, they extract DNA from a non-pathogenic strain of E.coli, from a strawberry and from their own cheeks. By doing the step-by-step procedure they understand that DNA lives inside the cell and that all species have DNA. They see the cloudy DNA precipitate in an ethanol solution. We conduct open discussions about the sequencing of the human genome.
Restriction Fragments
This module deals with the analysis of DNA fragments previously cut with restriction enzymes. Participants learn how to prepare agarose gels and how to perform DNA electrophoresis. By comparing patterns of digestion obtained with different enzymes they comprehend the specificity of the restriction enzyme. This concept is used to explain the "biological meaning" of restriction enzymes as the most primitive endogenous immune system and how scientists use this feature to create recombinant organisms Participants learn how to read restriction maps and how restriction enzymes are applied to the molecular diagnosis of genetic disease. We promote discussions of issues related to genetic tests such as privacy, individuality, and genetic counseling.
Bacteria Transformation
In this module, a recombinant non-pathogenic strain of E.coli is created by the introduction of a foreign gene inside the bacteria. A new clone of recombinant bacteria is replicated and propagated in a Petri dish. In this module, participants observe the formation of blue colonies due to the activation and transcription of the lacZ gene, a gene that takes part in the lactose promoter system. This module offers a unique opportunity to experience a visible result of a molecular event. We promote discussions about recombinant organisms, bio-hazardous and cloning.
An Introduction to Bioinformatics
Using an interactive multimedia CD-ROM produced by DNA goes to SchoolTM basic concepts of bioinformatics as well as demonstrations of how to use bioinformatic tools available in the Internet are provided. Participants are taken through a virtual tour to the GenBank and other databases. They learn how to analyze and compare DNA sequences.
Multiplying our DNA
In this advanced module, participants extract their own DNA from their cheeks using swabs. The DNA of each individual will be used to perform a PCR assay. A small piece of their genome will be amplified several times. The area to be amplified varies in size among individuals so they can see the genetic variability that exists between individuals. It is important to mention that this area of the genome is not associated with any functional gene and is not implicated in disease or susceptibility trait.